Walk down any pharmacy aisle and the active ingredient labels repeat in patterns most consumers never notice. For the formulators behind those labels, supply for these molecules has gotten harder, not easier, over the last five years. Download our line cards here. OTC Active Ingredients and the Sourcing Reality Since 2020 Guaifenesin, dextromethorphan, diphenhydramine, phenylephrine, and the chlorpheniramine and brompheniramine family form the backbone of nearly every OTC col